Japanese encephalitis — JE virus, JEV, symptoms and prevention (2024)

Key facts

  • Japanese encephalitis is a serious disease caused by the Japanese encephalitis virus (JEV).
  • Humans can catch JEV if they are bitten by infected mosquitoes.
  • Fewer than 4% of people who catch JEV will experience symptoms.
  • For people who have symptoms, Japanese encephalitis can cause death or nervous system complications.
  • You can reduce your risk of Japanese encephalitis by avoiding mosquito bites and getting vaccinated against JEV.

What is Japanese encephalitis?

Japanese encephalitis is an infection that can affect the central nervous system and cause serious complications and even death.

It is endemic (regularly found) in parts of Asia and the Torres Strait region of Australia.

Before 2021, only five cases of Japanese encephalitis had been seen in mainland Australia.

However, between January 2021 and February 2023, 45 people on mainland Australia were diagnosed with Japanese encephalitis. During this outbreak, 7 people died.

An emergency response to this outbreak involved:

  • vaccination of at-risk people
  • raising public awareness of Japanese encephalitis

As of June 2023, the emergence response to Japanese encephalitis was no longer needed at this time.

What are the symptoms of Japanese encephalitis?

Most people with Japanese encephalitis don’t experience any symptoms.

Less than 4 in 100 people with Japanese encephalitis will have any symptoms.

You may notice symptoms about 5 to 15 days after being bitten by a JEV-infected mosquito.

The Japanese encephalitis virus can cause encephalitis and meningitis.

These conditions are serious, and can cause symptoms such as:

  • fever
  • headache
  • neck stiffness
  • vomiting
  • convulsions and seizures (fits)
  • muscle weakness and paralysis
  • fatigue and coma

JEV can also make you feel confused or agitated.

CHECK YOUR SYMPTOMS — Use the Symptom Checker and find out if you need to seek medical help.

What causes Japanese encephalitis?

Japanese encephalitis is caused by the Japanese encephalitis virus (JEV).

JEV only spreads to humans via bites from infected mosquitoes.

Animals such as pigs, waterbirds and horses can also catch JEV. These animals can’t transfer the virus to humans. If you work closely with these animals — especially pigs — you’re at increased risk of being bitten by an infected mosquito.

You also cannot catch JEV:

  • through contact with infected people
  • by eating meat from an infected animal

When should I see my doctor?

If you have recently been in an area with reports of JEV, and you experience sudden symptoms, seek medical attention.

If you think you may have Japanese encephalitis, visit your nearest emergency department or call an ambulance on triple zero (000).

FIND A HEALTH SERVICE — The Service Finder can help you find doctors, pharmacies, hospitals and other health services.

How is Japanese encephalitis diagnosed?

Your doctor can diagnose Japanese encephalitis by asking you about your symptoms. They may also ask if you have recently travelled to any areas where there are cases of JEV.

If your doctor thinks you have Japanese encephalitis, further tests can confirm your diagnosis. These may include a:

  • blood test
  • lumbar puncture (spinal tap)

How is Japanese encephalitis treated?

There is no specific medicine or treatment for Japanese encephalitis.

If you have symptoms of Japanese encephalitis, you will likely need treatment in hospital to manage:

  • seizures
  • encephalitis
  • meningitis

Antibiotics will not help you recover because this illness is caused by a virus, not bacteria.

Can Japanese encephalitis be prevented?

The 2 best ways to prevent Japanese encephalitis are to:

  1. avoid being bitten by mosquitoes, especially in areas where JEV is common
  2. get vaccinated against JEV

What are the recommendations for the JEV vaccination?

Vaccination is a safe and effective way to reduce your chance of catching JEV.

Vaccination is recommended for people who:

  • spend a month or more in Asia or the Torres Strait region of Australia during the wet season
  • work in laboratories with JEV
  • work with mosquitoes
  • work with pigs

See the table below for details about the Japanese encephalitis vaccination.

How many types of vaccines are available?

2 types of vaccines against JEV are currently available in Australia.

When to get vaccinated?

All people over 2 months of age can get a JEV vaccine.

You should be vaccinated before you spend 1 month or more in Asia or the Torres Strait region of Australia in the wet season.

How many doses are required?

1 or 2 doses. The number of doses and time between doses will depend on:

  • the type of vaccine recommended for you
  • your age
  • your risk of getting JEV
How is it administered?

Injection

Is it free?

No — there is a cost.

Common side effects

The vaccine is very safe. Side effects are mild and temporary. They may include:

  • a sore arm
  • swelling where the needle went in
  • headache
  • fatigue

You can talk to your doctor about which vaccine is best for you or your child.

If you're not sure whether you should get vaccinated, you can ask your:

  • doctor
  • travel clinic

How can mosquito bites be avoided?

To protect yourself from mosquito bites, you can try these things:

  • Reduce skin exposure and avoid tight clothes. Instead, wear loose-fitting clothes such as long-sleeved shirts, long pants, long socks and enclosed footwear.
  • Avoid spending time outside at dawn or dusk, as this is when mosquitoes are most active.
  • Use insect repellent. Choose products that contain diethyltoluamide (DEET), picaridin or lemon eucalyptus oil — these are most effective against mosquitoes.
  • Stay in rooms that have flyscreens over the doors and windows.
  • Sleep in rooms that have mosquito nets.
  • Do not leave water containers open. Mosquitoes breed in stagnant water.

You can find out more about insect bites here.

How is the spread of Japanese encephalitis prevented?

Japanese encephalitis is a nationally notifiable disease in Australia. This means, if you are diagnosed with Japanese encephalitis, your doctor will let your local public health authority know. They will check who you have been in contact with and take steps to control an outbreak.

Are there complications of Japanese encephalitis?

Japanese encephalitis can cause severe complications or death. Complications of Japanese encephalitis include permanent injury to your brain or nervous system.

About half of people who survive symptomatic Japanese encephalitis experience complications.

Resources and support

You can visit the Department of Health and Aged Care website for more information about Japanese encephalitis.

For information relevant to your state and territory click on the links below:

For more information on staying safe from JEV while travelling, you can:

If you need advice on JEV, call healthdirect on 1800 022 222 to speak with a registered nurse, 24 hours, 7 days a week (known as NURSE-ON-CALL in Victoria).

Japanese encephalitis — JE virus, JEV, symptoms and prevention (2024)

FAQs

How can you prevent the JE virus? ›

The best way to prevent Japanese encephalitis virus infection is to protect yourself from mosquito bites. Use insect repellent, wear long-sleeved shirts and pants, treat clothing and gear, and get vaccinated before traveling, if vaccination is recommended for you.

What are the symptoms of JEV virus? ›

What are the symptoms of Japanese encephalitis?
  • fever.
  • headache.
  • neck stiffness.
  • vomiting.
  • convulsions and seizures (fits)
  • muscle weakness and paralysis.
  • fatigue and coma.

Can Japanese encephalitis be cured? ›

There is no cure for the disease. Treatment is focused on relieving severe clinical signs and supporting the patient to overcome the infection. Safe and effective vaccines are available to prevent JE.

Can you fully recover from Japanese encephalitis? ›

Unfortunately, mortality for patients who do develop encephalitis is 20% to 30%. While most cases will improve in 6 to 12 months, many patients who survive will have significant neurologic and psychiatric sequelae (30% to 50% of cases).

Is there a way to prevent encephalitis? ›

These measures can help prevent certain types of infectious encephalitis: Keep your vaccinations up to date, especially when traveling to areas known to have encephalitis-causing viruses. Use proper hygiene and hand-washing to help prevent the spread of viruses and bacteria. Avoid mosquito and tick exposure.

How to flush out a viral infection? ›

Most viral infections can be treated with home care. This may include drinking lots of fluids and taking over-the-counter pain medicine. You will probably feel better in 4 to 10 days. Antibiotics are not used to treat a viral infection.

What is the survival rate for JEV? ›

30% mortality rate. However, humans are incidental (dead-end) hosts. Amplification of JEV in swine often precedes human epidemics.

How long does JEV last? ›

Most adults will still have protection against JEV at 5 years after vaccination. If vaccinated as part of the 2022/23 JEV Vaccination Program, no further doses are recommended.

Is it worth getting the Japanese encephalitis vaccine? ›

The Japanese encephalitis vaccine is most highly recommended for anyone traveling for one month or longer to endemic areas in Asia and Papua New Guinea, especially during the virus transmission season.

How rare is Japanese encephalitis? ›

The global incidence of JE is unknown. However, it is estimated that 68,000 clinical cases occur every year in 24 JE endemic countries in the Southeast Asia and Western Pacific regions [2].

What is the incubation period of JE? ›

In persons who develop symptoms of Japanese encephalitis (JE), the time from infection until illness onset (incubation period) is typically 5–15 days. Initial symptoms often include fever, headache, and vomiting. Disorientation, weakness, and coma might develop over the next few days.

What are the stages of Japanese encephalitis? ›

When the course is one of encephalitis, the illness can be divided into three stages – prodromal, acute encephalitic, and a convalescent stage. The affliction starts abruptly with high fever. Headache, vomiting, and diarrhea may occur.

How contagious is Japanese encephalitis? ›

It is spread when a mosquito bites an animal (such as pigs or waterbirds) that has the Japanese encephalitis virus and then this mosquito bites a human. Humans are not able to give Japanese encephalitis virus to other humans.

When is Japanese encephalitis season? ›

In temperate areas of Asia, JE virus transmission is seasonal. Human disease usually peaks in the summer and fall. In the subtropics and tropics, transmission can occur year-round, often with a peak during the rainy season.

Where is Japanese encephalitis commonly found? ›

Japanese encephalitis virus is present in Asia and Oceania, from Japan to India, Pakistan and Australia. Outbreaks are erratic and spatially and temporally limited phenomena, occurring quite unpredictably. The virus is a leading cause of viral encephalitis in Asia, with 30 000 to 50 000 cases reported annually.

What are the preventions of Marburg virus? ›

Avoid contact with blood and body fluids (such as urine, feces, saliva, sweat, vomit, breast milk, amniotic fluid, sem*n, and vagin*l fluids) of people who are sick. Avoid contact with sem*n from a person who has recovered from MVD, until testing shows that the virus is gone from their sem*n.

Can Japanese encephalitis be prevented by vaccine? ›

Japanese encephalitis is a rare but serious infection you can get from mosquito bites in some parts of the world. If you're travelling to an area where there's a risk of catching it, you can get a vaccine to help prevent it.

What are methods to prevent St Louis encephalitis? ›

Use insect repellent containing DEET, picaridin, IR3535 or oil of lemon eucalyptus on exposed skin and/or clothing. The repellent/insecticide permethrin can be used on clothing to protect through several washes. Always follow the directions on the package. Wear long sleeves and pants when weather permits.

How can you prevent viruses? ›

Core Prevention Strategies
  1. Stay up to date with COVID-19 vaccines. ...
  2. Practice good hygiene (practices that improve cleanliness)
  3. Take steps for cleaner air.
Apr 4, 2024

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