Latex Allergy A Prevention Guide (98-113) | NIOSH (2024)

1998
DHHS (NIOSH) Publication Number 98-113

Latex Allergy A Prevention Guide (98-113) | NIOSH (1)

Latex gloves have proved effective in preventing transmission of many infectious diseases to health care workers. But for some workers, exposures to latex may result in allergic reactions. Reports of such reactions have increased in recent years–especially among health care workers.

What is latex?

In this pamphlet, the term “latex” refers to natural rubber latex, the product manufactured from a milky fluid derived from the rubber tree, Hevea brasiliensis. Several types of synthetic rubber are also referred to as “latex,” but these do not release the proteins that cause allergic reactions.

What is latex allergy?

Latex allergy is a reaction to certain proteins in latex rubber. The amount of latex exposure needed to produce sensitization or an allergic reaction is unknown. Increasing the exposure to latex proteins increases the risk of developing allergic symptoms. In sensitized persons, symptoms usually begin within minutes of exposure; but they can occur hours later and can be quite varied. Mild reactions to latex involve skin redness, rash, hives, or itching. More severe reactions may involve respiratory symptoms such as runny nose, sneezing, itchy eyes, scratchy throat, and asthma (difficult breathing, coughing spells, and wheezing). Rarely, shock may occur; however, a life-threatening reaction is seldom the first sign of latex allergy.

Who is at risk of developing latex allergy?

Health care workers are at risk of developing latex allergy because they use latex gloves frequently. Workers with less glove use (such as housekeepers, hairdressers, and workers in industries that manufacture latex products) are also at risk.

Is skin contact the only type of latex exposure?

No. Latex proteins become fastened to the lubricant powder used in some gloves. When workers change gloves, the protein/powder particles become airborne and can be inhaled.

How is latex allergy treated?

Detecting symptoms early, reducing exposure to latex, and obtaining medical advice are important to prevent long-term health effects. Once a worker becomes allergic to latex, special precautions are needed to prevent exposures. Certain medications may reduce the allergy symptoms; but complete latex avoidance, though quite difficult, is the most effective approach.

Are there other types of reactions to latex besides latex allergy?

Yes. The most common reaction to latex products is irritant contact dermatitis– the development of dry, itchy, irritated areas on the skin, usually the hands. This reaction is caused by irritation from wearing gloves and by exposure to the powders added to them. Irritant contact dermatitis is not a true allergy. Allergic contact dermatitis (sometimes called chemical sensitivity dermatitis) results from the chemicals added to latex during harvesting, processing, or manufacturing. These chemicals can cause a skin rash similar to that of poison ivy.

How can I protect myself from latex allergy?

Take the following steps to protect yourself from latex exposure and allergy in the workplace:

  1. Use nonlatex gloves for activities that are not likely to involve contact with infectious materials (food preparation, routine housekeeping, general maintenance, etc.).
  2. Appropriate barrier protection is necessary when handling infectious materials. If you choose latex gloves, use powder-free gloves with reduced protein content.
    • Such gloves reduce exposures to latex protein and thus reduce the risk of latex allergy.
    • So-called hypoallergenic latex gloves do not reduce the risk of latex allergy. However, they may reduce reactions to chemical additives in the latex (allergic contact dermatitis).
  3. Use appropriate work practices to reduce the chance of reactions to latex.
    • When wearing latex gloves, do not use oil-based hand creams or lotions (which can cause glove deterioration).
    • After removing latex gloves, wash hands with a mild soap and dry thoroughly.
    • Practice good housekeeping: frequently clean areas and equipment contaminated with latex-containing dust.
  4. Take advantage of all latex allergy education and training provided by your employer and become familiar with procedures for preventing latex allergy.
  5. Learn to recognize the symptoms of latex allergy: skin rash; hives; flushing; itching; nasal, eye, or sinus symptoms; asthma; and (rarely) shock.

What if I think I have latex allergy?

If you develop symptoms of latex allergy, avoid direct contact with latex gloves and other latex-containing products until you can see a physician experienced in treating latex allergy.

If you have latex allergy, consult your physician regarding the following precautions:

  • Avoid contact with latex gloves and products.
  • Avoid areas where you might inhale the powder from latex gloves worn by other workers.
  • Tell your employer and health care providers (physicians, nurses, dentists, etc.) that you have latex allergy.
  • Wear a medical alert bracelet.

Additional Information

For additional information about latex allergy, or to request a copy of NIOSH Alert No. 97-135, Preventing Allergic Reactions to Natural Rubber Latex in the Workplace, call 1-800-35-NIOSH (1-800-356-4674)

You may also visit the NIOSH Homepage

To access latex allergy websites, select Latex Allergy through the NIOSH Homepage, or access the websites directly at the following locations:

* Second printing, with minor changes for clarity.

Latex Allergy A Prevention Guide

Latex Allergy A Prevention Guide (98-113) | NIOSH (2024)

FAQs

What is level 1 latex allergy? ›

Immediate type I hypersensitivity reactions are immunoglobulin E (IgE)-mediated responses to latex proteins, and can range from urticaria to anaphylaxis. Type I reactions should be considered in patients who have immediate skin symptoms on contact with latex gloves.

What is the most reliable test for latex allergy? ›

Diagnostic Tests

The two most common methods used to identify specific IgE antibody are the percutaneous (prick) skin test and radioallergosorbent test (RAST). Skin testing to identify latex-specific IgE antibody is convenient, sensitive, and fast.

What are the three types of latex allergies? ›

There are three types of latex reactions:
  • Irritant contact dermatitis. This is the least-threatening type, and it's not an allergic skin reaction. ...
  • Allergic contact dermatitis. This is a delayed reaction to additives used in latex processing. ...
  • Immediate allergic reaction (latex hypersensitivity).
Sep 10, 2022

What percent is allergic to latex? ›

Less than 1 percent of the general population is reported to have a reaction to latex. Despite this, more than 1,700 cases of latex allergy have been reported to the U.S. Food and Drug Administration (FDA) since 1988. Many more cases probably go unreported.

What does a Class 1 allergy mean? ›

Class 1 food allergens (eg, milk, egg, or peanut) are oral allergens that cause sensitization via the gastrointestinal tract. 28. Class 2 food allergens are aeroallergens (eg, major birch pollen allergen Bet v 1) that cause sensitization via the respiratory tract.

What is the code for latex allergy test? ›

LOINC Map
Order Code
670654
Order Code NameAllergen Profile, Latex Plus
Result Code602669
Result Code NameK082-IgE Latex
31 more rows

How do I know if I have a mild latex allergy? ›

Symptoms of latex allergy
  1. dermatitis.
  2. itchy skin.
  3. crusty skin lesions.
  4. lesions that are irritated by sweat and friction.
  5. hay fever symptoms, such as running nose and itchy eyes when latex is inhaled.
  6. sneezing.
  7. coughing.
  8. wheezing and breathing difficulties.

Will Benadryl help latex allergy? ›

Antihistamines block the action of histamine, a chemical released by the body in response to an allergen. They can help relieve some of the symptoms associated with a latex allergy including sneezing, itching, hives, and nasal congestion.

Can a latex allergy go away? ›

Although medicines are available to reduce the symptoms of latex allergy, there is no cure. The only way to prevent a latex allergic reaction is to avoid products that contain latex. Despite your best efforts to avoid latex, you may come into contact with it.

What foods should I avoid if I have a latex allergy? ›

Here are some of the foods you may react to if you have a latex allergy:
  • Most common: Avocado. Banana. Bell pepper. Chestnut. Fig. Kiwi. Peach. Tomato.
  • Less common: Apricot. Celery. Coconut. Mango. Papaya. Passion fruit. Pineapple. Spinach. Strawberry.

Do eggs contain latex? ›

Some food contains similar proteins and can cause what is known as latex-fruit reactions. As the name suggests, a latex-fruit reaction can occur with certain fruits and vegetables with seeds. Animal products (meat, dairy, and eggs) will not cause this reaction and are generally safe for people with latex allergies.

Is banana allergy the same as latex allergy? ›

A banana allergy is often connected to a latex allergy. This is because some of the proteins in the rubber trees that produce latex are known to cause allergies, and they are similar to the proteins found in some nuts and fruits, including bananas. This syndrome is known as latex-food syndrome or latex-fruit allergy.

What item used in hospitals is the most likely to contain latex? ›

Medical items that may include latex include: surgical and exam gloves. IV tubing injection sites. catheters.

What is stage1 latex allergy? ›

Latex allergy (Type I) symptoms range from skin irritation to respiratory symptoms to life-threatening anaphylaxis – and there's no way to predict which will occur if exposed. Symptoms of latex allergy may be mild at first, progressing to more serious types of symptoms. Symptoms of latex allergy include: skin redness.

Who is at highest risk for a latex allergy? ›

People who are at higher risk for developing latex allergy include: Health care workers and others who frequently wear latex gloves. People who have had multiple surgeries (for example, 10 or more), such as children with spina bifida. People who are often exposed to natural rubber latex, including rubber industry ...

What is a Type 1 sensitivity allergy? ›

Type I hypersensitivity is also known as an immediate reaction and involves immunoglobulin E (IgE) mediated release of antibodies against the soluble antigen. This results in mast cell degranulation and release of histamine and other inflammatory mediators.

How is Question 1 latex allergy diagnosed? ›

Latex allergy is diagnosed using a number of tests including: medical history. physical examination. allergy testing, including skin prick tests and blood tests.

What is Type 1 hypersensitivity to latex? ›

Latex allergy is an immediate (type I) hypersensitivity reaction to the milky sap of cultured rubber trees (Hevea brasiliensis). With type I reactions, antigen enters the body to promote the genesis of immunoglobulin E (IgE) antibodies, which attach to mast cells.

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