Peripheral nerve injuries - Diagnosis and treatment (2024)

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Diagnosis

To diagnose peripheral nerve injuries, your healthcare professional reviews your medical history. You're asked about any accidents or previous surgeries you've had and about your symptoms. Your healthcare professional also conducts a physical and neurological exam. If there are symptoms of a nerve injury, you may need diagnostic tests, which may include:

  • Electromyography (EMG). In an EMG, a thin-needle electrode inserted into the muscle records the muscle's electrical activity at rest and in motion. Reduced muscle activity can suggest nerve injury.
  • Nerve conduction study. Electrodes placed at two different points in the body measure how well electrical signals pass through the nerves.
  • Magnetic resonance imaging (MRI). MRI uses a magnetic field and radio waves to produce detailed images of areas affected by nerve damage.
  • Ultrasound. Like MRI, these high-frequency sound waves produce detailed images of the area affected by nerve damage.

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Treatment

If a nerve is injured but not cut, the injury is more likely to heal. Injuries in which a nerve has been completely cut are harder to treat, and recovery may not be possible.

Your treatment is based on the extent and cause of your injury and how well the nerve is healing.

  • If your nerve is healing properly, you may not need surgery. You may need to rest the affected area until it's healed. Nerves recover slowly, and maximal recovery may take many months or several years.
  • Regular checkups allow your healthcare professional to make sure your recovery is on track.
  • If your injury is caused by a medical condition, your healthcare professional treats the condition.
  • Depending on the type and severity of your nerve injury, you may need medicines such as aspirin or ibuprofen (Advil, Motrin IB, others) to relieve your pain. Medicines used to treat depression, seizure or insomnia may be used to relieve nerve pain. Some people with peripheral nerve injuries may need corticosteroid injections for pain relief.
  • Your healthcare professional may recommend physical therapy to prevent stiffness and restore function.

Surgery

If your injury does not seem to be healing properly, you may need surgery. A surgeon can use EMG testing in the operating room to assess whether scarred nerves are recovering. Doing an EMG test directly on the nerve is more accurate and reliable than doing the test over the skin.

Sometimes a nerve sits inside a tight space similar to a tunnel or is squeezed by scarring. When this happens, a surgeon may enlarge the tight space or free the nerve from the scar.

If a section of an injured nerve is cut completely or damaged beyond repair. A surgeon can remove the damaged section and directly reconnect healthy nerve ends. This is known as nerve repair. Or the surgeon may implant a piece of nerve from another part of the body to close a gap between the nerves. This is known as a nerve graft. These procedures can help nerves regrow.

Peripheral nerve graft

Peripheral nerve injuries - Diagnosis and treatment (1)

Peripheral nerve graft

To repair a damaged nerve, a surgeon removes a small part of the sural nerve in the leg and implants this nerve at the site of the repair.

Sometimes the surgeon can use another working nerve to make an injured nerve work, known as nerve transfer.

Peripheral nerve transfer

Peripheral nerve injuries - Diagnosis and treatment (2)

Peripheral nerve transfer

Your surgeon can bypass a damaged section of nerve by connecting a healthy nerve to restore function.

If you have a serious nerve injury, surgery can restore function to critical muscles by transferring tendons from one muscle to another.

Restoring function

A number of treatments can help restore function to the affected muscles.

  • Braces or splints. These devices keep the affected limb, fingers, hand or foot in the proper position to improve muscle function.
  • Electrical stimulator. Stimulators can activate muscle served by an injured nerve while the nerve regrows. However, this treatment may not be effective for everyone. Your healthcare professional can discuss electrical stimulation with you if it's an option.
  • Physical therapy. Therapy involves specific movements or exercises to keep affected muscles and joints active. Physical therapy can prevent stiffness and help restore function and feeling.
  • Exercise. Exercise can help improve muscle strength, maintain range of motion and reduce muscle cramps.

Clinical trials

Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.

Preparing for your appointment

Many tests may be used to help diagnose the type and severity of peripheral nerve injury. When you make your appointment, be sure to ask whether you need to prepare for these tests. For instance, you may need to stop taking certain medicines for a few days or avoid using lotions the day of the test.

If possible, take along a family member or friend. Sometimes it can be difficult to absorb all the information you're given during an appointment. Someone who accompanies you may remember something that you forgot or missed.

Other suggestions for getting the most from your appointment include:

  • Write down all your symptoms, including how you were injured, how long you've had your symptoms and whether they've gotten worse over time.
  • Make a list of all medicines, vitamins and supplements that you take.
  • Ask questions. Children and adults with peripheral nerve injuries have several options for restoring lost function. Be sure to ask about all the treatments available to you or your child. If you run out of time, ask to speak with a nurse or have your healthcare professional call you later.

By Mayo Clinic Staff

Peripheral nerve injuries care at Mayo Clinic

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March 30, 2024

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  1. Peripheral neuropathy. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/health-information/disorders/peripheral-neuropathy. Accessed Jan. 26, 2024.
  2. Nerve injuries. American Academy of Orthopaedic Surgeons. https://orthoinfo.aaos.org/topic.cfm?topic=A00016. Accessed Feb. 28, 2022.
  3. Rutkove SB. Overview of upper extremity peripheral nerve syndromes. https://www.uptodate.com/contents/search. Accessed Feb. 28, 2022.
  4. Rutkove SB. Overview of lower extremity peripheral nerve syndromes. https://www.uptodate.com/contents/search. Accessed Feb. 28, 2022.
  5. Cervical radiculopathy (pinched nerve). American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=a00332. Accessed Jan. 29, 2024.
  6. Azar FM, et al. Peripheral nerve injuries. In: Campbell's Operative Orthopaedics. 14th ed. Elsevier; 2021. https://www.clinicalkey.com. Accessed Feb. 28, 2022.
  7. Daroff RB, et al. Trauma of the nervous system: Peripheral nerve trauma. In: Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed Feb. 28, 2022.
  8. Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. https://catalog.ninds.nih.gov/publications/neurological-diagnostic-tests-and-procedures. Accessed Jan. 26, 2024.
  9. Neligan PC. Peripheral nerve injuries of the upper extremity. In: Plastic Surgery. Elsevier; 2018. https://www.clinicalkey.com. Accessed Feb. 28, 2022.
  10. Pain. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Hope-Through-Research/Pain-Hope-Through-Research. Accessed Jan. 26, 2024.
  11. Brachial plexus injuries. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/Disorders/All-Disorders/Brachial-Plexus-Injuries-Information-Page. Accessed Jan. 26, 2024.
  12. Lopes B, et al. Peripheral nerve injury treatments and advances: One health perspective. International Journal of Molecular Sciences. 2022; doi:10.3390/ijms23020918.
  13. Juckett L, et al. The effect of electrical stimulation on nerve regeneration following peripheral nerve injury. Biomolecules. 2022; doi:10.3390/biom12121856.
  14. Strommen JA, et al. Neurophysiology during peripheral nerve surgery. Handbook of Clinical Neurology. 2022; doi:10.1016/B978-0-12-819826-1.00022-3.
  15. Ami TR. Allscripts EPSi. Mayo Clinic. Nov. 14, 2023.
  16. Naum R, et al. Autoimmune polyneuropathies. Handbook of Clinical Neurology. 2023; doi:10.1016/B978-0-323-98818-6.00004-2.
  17. Spinner RJ (expert opinion). Mayo Clinic. Feb. 15, 2024.

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  • Peripheral nerve graft
  • Peripheral nerve transfer

Peripheral nerve injuries

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Peripheral nerve injuries - Diagnosis and treatment (2024)

FAQs

How long does it take for peripheral nerves to heal? ›

If your nerve is bruised or traumatized but is not cut, it should recover over 6-12 weeks. A nerve that is cut will grow at 1mm per day, after about a 4 week period of 'rest' following your injury. Some people notice continued improvement over many months.

What is the best treatment for nerve damage? ›

If your nerve is only injured, you may recover over time without surgery. Nerves heal slowly, sometimes over many months. For these mild nerve injuries, nonsurgical treatment options include medication, physical therapy or massage therapy. Peripheral nerve surgery can reconstruct or repair damaged nerves.

How to heal the peripheral nervous system? ›

For mild nerve injuries, the following non-surgical treatments may be part of the plan:
  1. Acupuncture.
  2. Massage therapy.
  3. Medication.
  4. Orthotics.
  5. Physical therapy and rehabilitation.
  6. Weight loss.

What is the most appropriate diagnostic method for peripheral nerve injury? ›

This makes MRI a valuable tool for diagnosing complex cases where multiple nerves may be affected. Magnetic resonance imaging (MRI) can reveal pathological changes in peripheral nerves (35, 36, 40–45).

What is the life expectancy of someone with peripheral nerve damage? ›

Specifically, individuals with PN had an average life expectancy of 10.8 years, compared to 13.9 years for those without.

Which vitamin is best for nerve repair? ›

B vitamins like B12, B6, B3, B1 are essential for nerve health. These vitamins can help with the healing of nerve damage and relieve nerve damage symptoms like numbness and tingling—this is why they are called 'neurotropic' vitamins.

What drink is good for neuropathy? ›

Water should be a staple in any diet, and even more so for those looking to reduce nerve pain. It's critical to stay hydrated throughout the day to reduce inflammation and avoid triggering pain receptors. Aim to drink eight 8-oz. of water each day.

What stops nerve pain immediately? ›

Painkillers. For severe nerve pain, powerful opioid painkillers can help. Studies have found that for many types of nerve pain, they are as effective as anticonvulsants or antidepressants. Unlike other treatments for nerve pain, they also work very quickly.

What are signs that nerve damage is healing? ›

Nerves recover with a myriad of different symptoms. It is important to educate and understand the different situations of normal nerve recovery to provide comfort and re-assurance to the patient. Sharp, shooting, electric pains are normal signs of nerve recovery.

What is the strongest drug for nerve pain? ›

Anticonvulsants are one of the most effective medications for treating nerve pain. Examples include pregabalin (Lyrica) and gabapentin (Neurontin). These medications are typically very effective in treating nerve pain, but they may also cause undesired side effects, such as: lethargy.

How to wake up damaged nerves? ›

Recovery is a slow process, and the biggest thing you can do to regain nerve sensation and function is to move consistently. You may experience tingling feelings and possibly sensations similar to electrical shock, which is a good sign of having new sensitive nerves.

What is the best exercise for nerve damage? ›

4 Exercises to Reduce Chronic Nerve Pain
  • Go for a Walk. Aim to walk 30 minutes a day five days a week with a 20-minute stretch prior. ...
  • Low-Impact Aerobic Exercises. If kickboxing is not your style, take it easy with a nice afternoon of swimming or cycling. ...
  • Resistance Training. ...
  • Stretching Increases Flexibility.
Apr 4, 2017

Can peripheral nerve damage heal on its own? ›

Some damaged nerves heal on their own, but some injuries are too severe for the nerve to regrow. If a patient has a serious peripheral nerve injury, we have methods to restore muscle function that didn't exist 30 years ago. But it's also important to know there's often a ticking clock with nerve injuries.

What are signs of peripheral nerve regeneration? ›

The pain is a sign of irritation of the nerve; tingling is a sign of regeneration; or more precisely, tingling indicates the presence of young axons, in the process of growing.

Can you reverse peripheral nerve damage? ›

Usually a peripheral neuropathy can't be cured, but you can do a lot of things to prevent it from getting worse. If an underlying condition like diabetes is at fault, your healthcare provider will treat that first and then treat the pain and other symptoms of neuropathy.

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