Prebiotics vs. Probiotics: Can You Take Them Together? (2024)

Prebiotics and probiotics

Probiotics are bacteria that live in your body naturally and help your intestines break down food. Probiotics that are the same or very similar to the ones that your body makes can be taken to supplement healthy digestion. In recent years, a new class of supplements called prebiotics has been advertised as a companion to a probiotic regimen.

Prebiotics are made up of carbohydrates that your body can’t digest. They exist as food for the probiotic bacteria that you’re putting into your body. The use of prebiotics and probiotics together is called microbiome therapy. You don’t need to take a prebiotic for probiotics to work, but taking them might make your probiotics more effective.

Prebiotics don’t actually contain bacteria. They are fuel to help bacteria grow. All prebiotics are a type of dietary fiber. The fiber inulin, which is found in chicory root, bananas, and asparagus, is a prebiotic that can be used as food for gut bacteria. Onions, garlic, artichokes, and legumes are also prebiotic sources.

When a food source contains both prebiotics and probiotics, the combination is called a synbiotic. Foods that are synbiotics include cheese, kefir, and certain types of yogurt. Prebiotics can also be purchased as a commercial food additive or capsule supplement. They come in both liquid and powdered forms.

Prebiotics by themselves haven’t been found to be of much use. Recently, prebiotics added to infant formula were found to make the formula more closely resemble the health content of breastmilk. It’s only when used in conjunction that probiotics and prebiotics seem to have an effect.

When people talk about probiotic bacteria, they’re generally referring to two families of bacteria. Strains of Lactobacillus and Bifidobacterium are both associated with probiotic formulas. Many slightly fermented food products contain natural probiotics. Examples include sauerkraut, kimchi, and yogurt. Pickles are also a source of natural probiotics. Probiotics can be purchased as a food-grade health supplement. They come in a powder or liquid form. Probiotics usually need to be stored in the refrigerator to keep the bacteria contained in them alive and ready to reproduce.

In 2012, a study revealed that almost 4 million adults used probiotics for health. There is still more research needed to definitively identify the benefits of supplementing gut bacteria. However, research suggests that probiotics offer significant health benefits.

Some research indicates that prebiotics and probiotics are effective for treating diarrhea, irritable bowel syndrome, allergic disorders, and even the common cold. Prebiotics and probiotics have been suggested as treatments for obesity. They are being explored as a way to prevent the spread of cancer. Promising research has shown probiotics to be an effective treatment for inflammatory arthritis.

The Centers for Disease Control and Prevention (CDC) point out that the use of commercial prebiotics and probiotics is generally safe for healthy people. But there are rare instances where a healthy person becomes sick after ingesting certain types of bacteria contained in probiotics. Probiotics aren’t regulated according to “drug” standards by the U.S. Food and Drug Administration (FDA). This means that some of the live bacteria being used in probiotics hasn’t been evaluated according to strict safety measures. That’s something important to keep in mind when considering prebiotics and probiotics.

When you start a synbiotic regimen, there are some common side effects. Gas, constipation, loose stool, and loss of appetite sometimes happen, especially at the beginning of the regimen. Bloating and acid reflux have also been reported.

There is one side effect of probiotics that is known to be dangerous: having an allergic reaction to the bacteria that are being added to your body. If you break out in hives or experience extreme stomach pain after ingesting a prebiotic or probiotic, stop taking the supplement. Contact a doctor to determine if you’re having a reaction.

Sometimes probiotics are recommended for children that are taking antibiotics. But you should talk to your child’s doctor before you give probiotics to a child under the age of 12. Probiotics and prebiotics are also believed to be generally safe during pregnancy and breastfeeding. Get the all-clear from your doctor before beginning any new supplement during pregnancy and postpartum.

Every probiotic is different because of the variations in bacteria strains. Not all probiotics will work the same way for you, and not everyone needs to take a probiotic. If you are lactose intolerant, make sure you look for a dairy-free probiotic. If you have a yeast (Candida) overgrowth, you may want to be mindful of this and select a probiotic that doesn’t contain Candida.

People that are currently on antibiotic medication seem to benefit the most from a prebiotic and probiotic combination. The synbiotic effect helps combat the healthy bacteria that are being killed off while you take antibiotics.

Prebiotics vs. Probiotics: Can You Take Them Together? (2024)

FAQs

Prebiotics vs. Probiotics: Can You Take Them Together? ›

For most people, it's safe to take both types of supplements, and doing so may help maximize health benefits. You can take probiotics and prebiotics together daily, or you can take them at different times. As long as you're taking prebiotics and probiotics regularly, you'll likely get the benefits of both.

Can I take a probiotic and prebiotic together? ›

Yes, you can take prebiotics and probiotics together. This way, you can add new microbes to your gut with a probiotic while encouraging these microbes to grow and flourish with a prebiotic. Remember to talk with your doctor before making any permanent changes to your diet or supplement routine.

Should I take prebiotics or probiotics first? ›

You can take your prebiotic around the same time that you take your probiotic, but you'll want to space them out around 10 to 15 minutes. Otherwise, the two could interact too early, before they reach the large intestine which may lead to bloating. It's best to take your probiotic first, on an empty stomach.

How much probiotic and prebiotic should I take? ›

The number of CFU a person needs will ultimately depend on their purpose for taking probiotics. While most studies show that 10-20 million CFU are adequate for probiotic benefits, larger CFUs may be more suitable for individuals requiring significant support and/or seeking relief from certain health conditions.

What is a powerful combination of prebiotics and probiotics? ›

Some effective combinations might include prebiotic-rich foods like onions, garlic, bananas, and asparagus paired with probiotic-rich foods like yogurt, kefir, sauerkraut, and kombucha. It's essential to have a balanced intake of both to support the growth and activity of beneficial gut bacteria.

Should you take prebiotics in the morning or at night? ›

One factor to consider is that in the morning, prebiotics may have a smoother digestion route since your body is waking from an overnight fast. On the other hand, if you have a sensitive stomach (IBS besties, we see you!), taking prebiotics before bed allows you to sleep through any uncomfortable side effects.

What is the best prebiotic and probiotic combination? ›

The Best Probiotic + Prebiotic Combos on the Market
  • Best for Gut Health: Digestive Vibrance by Vibrant Health.
  • Best for Women's Urinary Tract: MegaFlora Women's Probiotic + Prebiotic by MegaFood.
  • Best for Mental Health: Dr. ...
  • Best for Healthy Skin: Skin Squad Pre+Probiotic by HUM Nutrition.
Jun 13, 2024

How long does it take for prebiotics and probiotics to start working? ›

Probiotics may be used to help manage a variety of conditions and symptoms. Depending on what you're taking probiotics for, you may see symptom improvements anywhere between a few days to a few months.

How do you know if prebiotics and probiotics are working? ›

If you're taking probiotics for a specific purpose, and the probiotics are working, you should be able to tell that you're feeling better. For example, if you're taking them to help relieve constipation or diarrhea, you should notice your poops becoming more regulated over time.

Which is more important, probiotics or prebiotics? ›

Keeping your gut bacteria balanced is important for many aspects of health. To do this, eat plenty of both prebiotic and probiotic foods, as they will help promote the most ideal balance between good and bad gut bacteria. Talk with your healthcare professional to ensure you're eating the right amounts of each.

Can you overdo prebiotics? ›

“If you take too many prebiotics in the form of supplements (like resistant starch, for example), then you will very likely get bloated, gassy, and uncomfortable with abdominal pain.

Can you overload your gut with probiotics? ›

Tamara Duker Freuman, a registered dietitian in New York, explains, “Different bacteria feed on different dietary compounds in the gut, and they produce gas as a byproduct.” An overload of probiotics may cause an interaction with the fiber, starch, and sugar in the gut, leading to gas, bloating, nausea, or diarrhea.

How long should you wait to eat after taking a prebiotic? ›

Probiotics are most effective when taken on an empty stomach. Taking probiotics at least 30 minutes before a meal will reduce the time it takes for the good bacteria to get to your gut. Probiotics are dietary supplements containing beneficial bacteria naturally occurring in your intestinal tract.

Is it OK to take prebiotics and probiotics together? ›

You can take prebiotics and probiotics together. Doing so is called microbiome therapy. Prebiotic fibers help feed and strengthen probiotic bacteria. Taking the two in combination can help make your probiotics more effective.

Is apple cider vinegar a prebiotic? ›

Apple cider vinegar contains prebiotics and probiotics. Both of these can support a healthy gut microbiome. The gut microbiome includes all the good bacteria in your gut that help with digestion — and keep the rest of your body running smoothly. First, ACV contains acetic acid that has prebiotic properties.

What should you take first prebiotic and a probiotic? ›

You can take your prebiotic around the same time that you take your probiotic, but you'll want to space them out around 10 to 15 minutes. Otherwise, the two could interact too early, before they reach the large intestine which may lead to bloating. It's best to take your probiotic first, on an empty stomach.

Should prebiotics and probiotics be taken on an empty stomach? ›

Taking them on an empty stomach is a good idea for most probiotics as it improves their survival rates through stomach acid. Many people take them first thing in the morning after waking up—about 30 minutes before breakfast or 2-3 hours after your last meal in the evening before bed.

What happens when you first start taking probiotics and prebiotics? ›

When first using probiotics, some people experience gas, bloating, or diarrhea. Changes in the gut microbiota can result in bacteria producing more gas than usual, which can lead to bloating. However, these side effects usually clear up within a few days or weeks of taking the probiotics.

Is it better to take probiotics morning or night? ›

Probiotics, like many other supplements, can be taken at any time of day, says Largeman-Roth. So, the best time to take probiotics is the time you'll remember to take them and stick to it. Most research on the probiotics does not compare timing, the experts note.

Should a woman take a probiotic and prebiotic daily? ›

Most need to be taken daily for the best results. There's a lot of research in progress on the potential benefits of probiotics, and initial results are promising. Different probiotic products may help improve your skin health, your vagin*l health or your gut health and build up your immunity in general.

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