What anxiety medications are not controlled substances?
- buspirone.
- tricyclic antidepressants.
- propranolol.
- pregabalin.
- hydroxyzine pamoate.
- SSRIs.
- SNRIs.
- Buspirone.
- Hydroxyzine.
- Gabapentin (Neurontin)
- Beta-Blockers.
- Psychotherapy.
- Cognitive Behavioral Therapy (CBT)
Certain medications used to treat anxiety disorders fall under the legal classification of “controlled substances.” Benzodiazepines, a class of medications commonly used for their tranquilizing and anti-anxiety effects, are considered a Schedule IV controlled substance.
Common Anxiety Medication Abuse
Specifically, the two most abused prescription drugs for anxiety are Valium and Xanax.
- SSRIs (antidepressants)
- SNRIs (antidepressants)
- Beta-Blockers (blood pressure medications)
- Buspirone (anti-anxiety)
- Hydroxyzine (brand name Vistaril, a prescription antihistamine).
Klonopin. Xanax and Klonopin are two of the most popular prescription anxiety medications available. They are both benzodiazepines, which slow down the central nervous system. They are used for treating generalized anxiety disorder, panic disorder, and sleep problems.
Selective serotonin reuptake inhibitors (SSRIs).
Generally safe with a low risk of serious side effects, SSRI antidepressants are typically recommended as the first choice of medications to treat panic attacks.
Schedule IV Controlled Substances
Examples of Schedule IV substances include: alprazolam (Xanax®), carisoprodol (Soma®), clonazepam (Klonopin®), clorazepate (Tranxene®), diazepam (Valium®), lorazepam (Ativan®), midazolam (Versed®), temazepam (Restoril®), and triazolam (Halcion®).
Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) are first-choice options for treating generalized anxiety disorder (GAD). If an SSRI or SNRI doesn't work, there are other options. These include buspirone and hydroxyzine.
No, Zoloft (sertraline) is not a controlled substance. It is in an antidepressant drug class known as selective serotonin reuptake inhibitors (SSRIs). Zoloft is commonly used to treat depression, anxiety, panic attacks and other mood disorders.
What drug do hospitals use for anxiety?
Midazolam. Midazolam (brand name: Versed) is a medication used to help ease anxiety. This medication is a Benzodiazepine, it belongs to the same family as Valium, and it can be given orally or intravenously.
First-line drugs are the selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors. Benzodiazepines are not recommended for routine use. Other treatment options include pregabalin, tricyclic antidepressants, buspirone, moclobemide, and others.

The National Institute for Health and Care Research (NIHR) Maudsley Biomedical Research Centre created a partnership with the pharmaceutical company Bionomics Ltd that has led to the development of BNC210 - a drug designed to reduce anxiety while avoiding the problems with existing treatments.
Commonly prescribed Alprazolam alternative antidepressant medications used to help with anxiety include Zoloft (sertraline), Prozac (fluoxetine), or Lexapro (escitalopram).
Taking Xanax can lead to misuse (abuse) and addiction of the medication, which can increase your risk of overdose and death.
Is Ativan stronger than Xanax? Neither drug is stronger than the other, but both are dosed differently due to how long they last in the body and how quickly they take effect. Is Ativan a benzo? Yes, Ativan is a benzodiazepine drug.
Herbal Alternatives to Xanax
It's recently been discovered that many traditional relaxing herbs work, in part, by increasing GABA. These include feverfew, passionflower, valerian, and lemon balm. These herbal remedies have been used for centuries as sleep aids and to bring about a state of relaxation.
Clonazepam is better to treat panic disorder than Xanax. The US Department of Veteran Affairs (VA) does not recommend using benzodiazepines for post-traumatic stress disorder (PTSD) as the medication can “cover-up” the feelings or trauma, and you may not ever learn how to manage your trauma.
Klonopin (clonazepam) | Sabril (vigabatrin) | Lamictal (lamotrigine) |
---|---|---|
More about Klonopin (clonazepam) | More about Sabril (vigabatrin) | More about Lamictal (lamotrigine) |
Generic Status | ||
Lower-cost generic is available | Lower-cost generic is available | Lower-cost generic is available |
Ratings & Reviews |
- Modafinil (Requires a Prescription)
Modafinil is a prescription drug often sold under the brand name Provigil that is used to treat uncontrollable drowsiness. It has been shown to provide mental stimulation similar to that which occurs with cocaine use but without the risk of dependence.
What is the best thing for anxiety attacks?
breathe in as slowly, deeply and gently as you can, through your nose. breathe out slowly, deeply and gently through your mouth. some people find it helpful to count steadily from 1 to 5 on each in-breath and each out-breath. close your eyes and focus on your breathing.
a type of antidepressant called a selective serotonin reuptake inhibitor (SSRI) or, if SSRIs are not suitable, a tricyclic antidepressant (usually imipramine or clomipramine) an anti-epilepsy medicine such as pregabalin or, if your anxiety is severe, clonazepam (these medicines are also beneficial for treating anxiety)
Buspirone is used to relieve anxiety, but it's not a first-choice medication. Your provider might consider adding on buspirone if your anxiety symptoms aren't well-controlled by other medications. It's taken by mouth, typically twice daily. Unlike some other anti-anxiety medications, it's not a controlled substance.
Bupropion is not a controlled substance.
Gabapentin is not a narcotic. It's not classified as a controlled substance in most states. (Kentucky, West Virginia, Michigan, Tennessee, and Virginia have reclassified gabapentin as a Schedule V controlled substance). Gabapentin is not an opioid.
Benzodiazepines help relieve anxiety by enhancing the activity of a neurotransmitter in the brain and generating a sedative effect. They work quickly, and can relieve anxiety for several hours. They are usually prescribed for those with generalized anxiety disorder, panic disorder, and social anxiety disorder.
A second therapeutic candidate, LYT-310 (oral cannabidiol), is expected to enter the clinic in Q4 of 2023. A second therapeutic candidate, LYT-310 (oral cannabidiol), is expected to enter the clinic in Q4 of 2023.
SSRIs. This group of drugs, including fluoxetine (Prozac), paroxetine (Paxil), fluvoxamine (Luvox), citalopram (Celexa), escitalopram (Cipralex) and sertraline (Zoloft), is usually the first choice for treatment of depression and anxiety disorders.
- Fluoxetine (Prozac®)
- Escitalopram (Lexapro®)
- Citalopram (Celexa®)
- Paroxetine (Paxil®)
- Sertraline (Zoloft®)
Non-controlled substances include over-the-counter medications and medications that are prescribed to treat medical conditions such as high blood pressure, diabetes, and bacterial infections.
What is the best anxiety medicine with least side effects?
Buspirone. This anti-anxiety medication may treat short- or long-term anxiety symptoms. Buspirone (BuSpar) works much more slowly than benzodiazepines and may not treat all types of anxiety disorder, but it causes fewer side effects and has a lower risk of dependency.
Buspirone is used to relieve anxiety, but it's not a first-choice medication. Your provider might consider adding on buspirone if your anxiety symptoms aren't well-controlled by other medications. It's taken by mouth, typically twice daily. Unlike some other anti-anxiety medications, it's not a controlled substance.
non-controlled substances? We can break prescription medications into two sub-categories: controlled and non-controlled. Most prescriptions for infections or for chronic conditions are non-controlled. For example, most blood pressure and cholesterol medications are non-controlled medications.
Gabapentin is not currently controlled under the Controlled Substances Act of 1970.
Prozac, or fluoxetine, is a Selective Serotonin Reuptake Inhibitor, also known as an SSRI. Prozac and other SSRIs are not considered narcotics (controlled substances), and the U.S. Drug Enforcement Administration doesn't consider it to have a high risk of addiction or abuse.
Is Hydroxyzine (Vistaril®, Atarax®) a controlled substance? No, Hydroxyzine (Vistaril®, Atarax®) is not a controlled substance. It is not habit forming, making it a great choice for anxiety and an alternative to benzodiazepines for some people.
Is Zoloft similar to Xanax? Zoloft and Xanax may have similar effects on mental health conditions and similar side effects, but they are different drugs. Zoloft is meant to be taken long-term, whereas Xanax is a short-term medication. Xanax is a controlled substance and can be habit-forming.
Commonly prescribed Alprazolam alternative antidepressant medications used to help with anxiety include Zoloft (sertraline), Prozac (fluoxetine), or Lexapro (escitalopram).
Clonazepam is a controlled substance. Prescriptions may be refilled only a limited number of times; ask your pharmacist if you have any questions.
Benzodiazepines (including diazepam, flunitrazepam and temazepam) Benzodiazepines are class C drugs. Some benzodiazepines belong to schedule 3 and some belong to schedule 4(1). Possession without a prescription, or supply or production without a licence, is illegal.