Remarkable ‘electronic nose’ could sniff out nerve gas and rotten foods simultaneously (2024)

During Black History Month, the National Science Foundation (NSF) asks the question: Which black scientists are poised to transform their field of research, or society? Analytical and environmental chemist Isiah Warner of Louisiana State University (LSU) is an example of an NSF-supported researcher working to do both.

For nearly 40 years, Warner's research has focused on fluorescence spectroscopy, a scientific method for studying how molecules interact with light in solutions such as a gas or liquid. Now, Warner and a team of LSU researchers are developing a new class of "electronic nose" that can more accurately detect hidden health, security and environmental concerns by simultaneously distinguishing and identifying the multiple volatile organic compounds (VOCs) that cause odors.

A freshly peeled orange has a distinctive odor. Other objects and even some medical conditions are also associated with distinctive odors. For example, the nitroglycerin fumes in dynamite can smell like banana, while food infected with salmonella bacteria can release hydrogen sulfide gas that smells like rotten eggs. The sweat from people suffering from schizophrenia may smell like vinegar.

These odors may help security personnel detect hazardous materials or explosives like dynamite. But what happens if dynamite is hidden amongst oranges? Could an electronic nose distinguish between multiple sources when the VOC mixture is complex?

Warner's answer uses a group of uniform materials based on organic salts (GUMBOS) to detect multiple VOCs simultaneously. By using GUMBOS with a tool called a quartz crystal microbalance, Warner's research team developed an enhanced capability to measure the amount and mass of molecules causing specific odors and identify the substances.

The technology could be useful for sniffing out environmental contaminants, petrochemicals, food contaminants, explosive vapors and disease biomarkers, among other hazardous materials. For example, the devices could be deployed in military clothing to provide real-time monitoring of volatile materials, such as nerve gas agents or other toxic vapors.

"It is possible to miniaturize this device for mobile use in less attractive environments than the laboratory," Warner says. "We believe that our studies will ultimately provide a very sophisticated electronic nose for determining and recognizing complex mixtures of VOCs."

Warner holds the highest professorial rank in the LSU system as a Boyd Professor. He is also the Philip W. West professor of analytical and environmental chemistry, and recently was named 2016 Southeastern Conference professor of the year.

Warner, who has served as principal or co-principal investigator on numerous NSF awards, has published more than 350 refereed publications in a variety of journals and conducted educational research focused on maintaining and enhancing student education in science, technology, engineering and mathematics. In 1997, Warner received the nation's highest award for exceptional STEM mentoring -- the Presidential Award for Excellence in Science, Mathematics and Engineering Mentoring (PAESMEM) award. NSF administers the award on behalf of the White House.

Remarkable ‘electronic nose’ could sniff out nerve gas and rotten foods simultaneously (2024)

FAQs

What is the electronic nose technology? ›

Bio-electronic noses use olfactory receptors – proteins cloned from biological organisms, e.g. humans, that bind to specific odor molecules. One group has developed a bio-electronic nose that mimics the signaling systems used by the human nose to perceive odors at a very high sensitivity: femtomolar concentrations.

How does the nose detect smell? ›

When you smell an odor, you're actually breathing in tiny molecules. These molecules stimulate specialized nerve cells, called olfactory sensory neurons, high inside the nose. There are a few million of these cells inside your nose.

Does nitroglycerin have an odor or smell? ›

For example, the nitroglycerin fumes in dynamite can smell like banana, while food infected with salmonella bacteria can release hydrogen sulfide gas that smells like rotten eggs.

When was the electronic nose invented? ›

Since the first report of an electronic nose based on chemical sensors and pattern recognition in 1982 [1], the instruments have experienced a significant development; they have been studied by several research groups over the world for a number of diverse possible applications in different sectors.

What is the electronic nose for food? ›

An electronic nose is such an instrument which consists of mechanism for identification of chemical detection such as an array of electronic sensors and a mechanism of pattern recognition.

Is there a device that can detect smells? ›

For odor measurement in smoking rooms and lavatories, detecting smell of medicines and foods, detecting odor from production process. For odor measurement in manufacturing and processing plants, detecting pet smell, measuring kitchen garbage and excrement odor.

Why do bad smells stay in your nose? ›

Sinusitis, mouth infections, and certain foods, drinks, and lifestyle habits are usually behind bad smells in the nose. People can usually get rid of bad smells in the nose by using home remedies, trying OTC medications, and making lifestyle changes.

What is the nerve in the nose? ›

Your olfactory nerve is the first cranial nerve (CN I). This nerve enables your olfactory system and sense of smell. Cranial nerve 1 is the shortest sensory nerve. It starts in your brain and ends in the upper, inside part of your nose.

How generally we detect smell of food through nose? ›

The taste buds of the tongue identify taste, and the nerves in the nose identify smell. Both sensations are communicated to the brain, which integrates the information so that flavors can be recognized and appreciated. Some tastes—such as salty, bitter, sweet, and sour—can be recognized without the sense of smell.

What is the smell of nitrate gas? ›

The term 'nitrogen oxides' (NOx) is usually used to include two gases-nitric oxide (NO), which is a colourless, odourless gas and nitrogen dioxide (NO2), which is a reddish-brown gas with a pungent odour.

What does glycerin smell like? ›

Vegetable glycerin, also known as glycerol or glycerine, is a clear liquid typically made from soybean, coconut or palm oils. It is odorless and has a mild, sweet taste with a syrup-like consistency. Vegetable glycerin is particularly popular in the cosmetic industry but has several other uses as well.

What does TNT smell like? ›

Baur recognized this new TNT smell as being similar to that of musk, showing that the scent could be easily and cheaply produced on a large scale. These nitro musks are still used today and are often used as the basis for many perfumes.

What are the smell sensors in the nose? ›

Your ability to smell comes from specialized sensory cells, called olfactory sensory neurons, which are found in a small patch of tissue high inside the nose. These cells connect directly to the brain. Each olfactory neuron has one odor receptor.

How accurate is the electronic nose? ›

Raw sensor signals from the electronic nose.

The Positive Predicted Value (PPV) was 83.0% (CI 95%: 67.4–92.3%) with a Negative Predictive Value (NPV) of 11.4% (CI 95%: 3.7–27.7%).

What is a sensor to detect odors? ›

An electronic nose is a device composed of an array of odour sensors with sensitivity to a wide range of chemical compounds. Reliable electronic nose systems rely on advanced data processing techniques. Among them, machine learning has become a core technique for electronic nose design.

What is the difference between human nose and electronic nose? ›

❖ E-noses have a series of sensors that correspond to components of an odor and analyzes its chemical makeup to identify it. ❖ They are much more sensitive than human noses as they have a greater number of receptor sensors with higher sensitivity.

What is the electronic nose in the military? ›

In the military, an electronic nose can be used to detect toxic chemicals and smoke compounds [50], determine indoor air quality [51–54], control automotive ventilation [55, 56], and measure water quality of an emergency water source (specific examples of detection of water quality: residues of cyanobacteria [57] and ...

What is electronic nose analysis technique? ›

Electronic nose is an analytical tool composed of an array of sensors (e.g. metal oxide, polymer) responding to volatile compounds with changes in their electrical properties. The combined pattern of these changes from all the sensors forms a fingerprint for the sample.

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