Signs You’re Low on Vitamin B12 (2024)

Signs You’re Low on Vitamin B12 (1)
Medically Reviewed by Dan Brennan,MD on April 13, 2022

Written by Paul Frysh

Signs You’re Low on Vitamin B12 (2)

Numbness

1/13

Do your hands, feet, or legs feel like they’re on “pins and needles”? Shortage of B12 can damage the protective sheath that covers your nerves. Diseases like celiac, Crohn’s, or other gut illnesses may make it harder for your body to absorb the vitamin. So can taking some heartburn drugs.

Signs You’re Low on Vitamin B12 (3)

You’re Colder Than Usual

2/13

Without enough B12, you might not have enough healthy red blood cells to move oxygen around your body (anemia). That can leave you shivering and cold, especially in your hands and feet.

Signs You’re Low on Vitamin B12 (4)

Brain Fog

3/13

A lack of B12 may lead to depression, confusion, memory problems, and dementia. It also can affect your balance. B12 supplements are usually safe. For adults, doctors recommend 2.4 micrograms a day. If you take more than what you need, your body passes the rest out through your pee. Still, high doses could have some side effects, like dizziness, headache, anxiety, nausea, and vomiting.

Signs You’re Low on Vitamin B12 (5)

Weakness

4/13

Your muscles may lack strength. You also might feel tired or lightheaded. Your doctor can check how much B12 is in your body, but not all of it may be useable. So it’s important to pay attention to any symptoms -- which can grow slowly or pop up more quickly -- and to alert your doctor.

Signs You’re Low on Vitamin B12 (6)

Smooth Tongue

5/13

Your doctor might call it atrophic glossitis. Tiny bumps on your tongue called papillae start to waste away. That makes it look and feel kind of smooth and glossy. Infections, medication, and other conditions can cause it, too. But if not enough B12 or other nutrients is to blame, your tongue also may be sore.

Herbivores Beware

6/13

B12 deficiency is rare because your body can store several years’ supply of the stuff. But plants don’t have any B12. So vegans and vegetarians who don’t eat any animal products should add some processed grains like fortified breads, crackers, and cereals.

Signs You’re Low on Vitamin B12 (8)

Heart Palpitations

7/13

This is when your heart suddenly races or skips a beat. You might feel it in your throat or neck. You can get more vitamin B12 from chicken, eggs, and fish. But one of best sources by far is something that may not be a regular on your menu: beef liver.

Signs You’re Low on Vitamin B12 (9)

Reason for Shortage: Age

8/13

As you get older, your body may not absorb B12 as easily. If you don’t treat it, low levels of B12 could lead to anemia, nerve damage, moodiness, and other serious problems. So watch for any symptoms, and get a blood test if your doctor recommends it.

Signs You’re Low on Vitamin B12 (10)

Reason for Shortage: Weight Surgery

9/13

One of the more common weight loss operations is called “gastric bypass.” After the surgery, food bypasses parts of your stomach and small intestine. That’s usually where B12 breaks down into usable form. Your doctor likely will monitor your B12 levels and suggest supplements or shots if you need them.

Signs You’re Low on Vitamin B12 (11)

Mouth Sores

10/13

You may get these ulcers on your gums or tongue. They could be a sign of low B12, anemia, or another condition. The sores usually clear up on their own, but it helps to avoid ingredients that might be irritating or painful, like vinegar, citrus, and hot spices like chili powder. Some over-the-counter medicines could soothe your pain.

Signs You’re Low on Vitamin B12 (12)

Reason for Shortage: Medications

11/13

Some drugs drop your B12 levels or make it harder for your body to use the vitamin. They include:

  • Chloramphenicol, an antibiotic used to treat infection
  • Proton pump inhibitors like lansoprazole (Prevacid) and omeprazole (Prilosec)
  • Peptic ulcer meds like cimetidine (Tagamet) and famotidine (Pepcid)
  • Metformin for diabetes.

Tell your doctor and pharmacist about all drugs and supplements you take.

Signs You’re Low on Vitamin B12 (13)

Digestive Woes

12/13

You might lose your appetite, drop too much weight, or have trouble pooping (constipation). If your B12 levels are low, your doctor will often inject it into a muscle to be sure your body absorbs it. Sometimes, high doses of pills work just as well. But remember that symptoms of B12 deficiency can be similar to signs of many other illnesses.

Signs You’re Low on Vitamin B12 (14)

Caution for Pregnant Vegetarians

13/13

Talk to your doctor about B12 supplements, both during pregnancy and breastfeeding. Infants who don’t get enough could have serious and permanent damage to their nerves or brain cells. Your baby might need supplements, too.

Signs You’re Low on Vitamin B12 (2024)

FAQs

Signs You’re Low on Vitamin B12? ›

Key points about vitamin B12 deficiency anemia

Without enough red blood cells, your tissues and organs don't get enough oxygen. Without enough oxygen, your body can't work as well. Symptoms include weak muscles, numbness, trouble walking, nausea, weight loss, irritability, fatigue, and increased heart rate.

How do you feel when your B12 is low? ›

Key points about vitamin B12 deficiency anemia

Without enough red blood cells, your tissues and organs don't get enough oxygen. Without enough oxygen, your body can't work as well. Symptoms include weak muscles, numbness, trouble walking, nausea, weight loss, irritability, fatigue, and increased heart rate.

What are the facial signs of B12 deficiency? ›

The deficiency of vitamin B12 can cause specific skin manifestations, such as hyperpigmentation, vitiligo, angular stomatitis, and hair and nail changes [1].

What are the four stages of B12 deficiency? ›

Stage 1: decreased levels of vitamin B12 in your blood. Stage 2: low levels of vitamin B12 in your cells along with metabolic abnormalities. Stage 3: neurological and psychological symptoms like anxiety, confusion, problems with balance, and others. Stage 4: macrocytic anemia – very large red blood cells ( 32 )

What blocks B12 absorption? ›

The main causes of B12 malabsorption include inherited disorders (Intrinsic factor deficiency, Imerslund-Gräsbeck disease, Addison's pernicious anemia, obesity, bariatric surgery and gastrectomies.

What happens if your B12 is low for too long? ›

If your anemia goes untreated for a long time, it can lead to heart failure. That's because your heart has to work harder. B12-related anemia may also raise the chances you'll have a heart attack, stroke, or other cardiovascular problem.

What are unusual symptoms of B12 deficiency? ›

Vitamin B12 deficiency can also cause symptoms that affect your brain and nervous system (neurological symptoms), including:
  • numbness.
  • muscle weakness.
  • psychological problems, which can range from mild depression or anxiety, to confusion and dementia.
  • problems with balance and coordination.
  • pins and needles.
  • incontinence.

What is clinically one of the first signs of vitamin B12 deficiency? ›

Neurological symptoms of vitamin B12 deficiency can include:

Numbness or tingling in your hands and feet. Vision problems. Having a hard time remembering things or getting confused easily. Having a difficult time walking or speaking like you usually do.

What color is your skin when you have a B12 deficiency? ›

A vitamin B12 deficiency can lead to pale skin and yellowing of the skin, called jaundice. These changes in skin color can develop when a person's body is unable to produce enough RBCs. Without enough RBCs, the skin may look pale. Vitamin B12 plays a role in the production of red blood cells.

Does B12 affect bowel movements? ›

Does vitamin B12 affect your bowel movements? Low vitamin B12 levels may cause diarrhea or constipation. Additionally, a lack of vitamin B12 can prevent your red blood cells from providing enough oxygen to your digestive tract. This can lead to nausea, vomiting, gas, and bloating.

What organ is affected by B12 deficiency? ›

The consequences and severity of B12 deficiency are variable depending on the degree of deficiency and its duration. Major organ systems affected include the blood, bone marrow and nervous system.

What is the gait of a B12 deficiency? ›

The Mayo Clinic describes the walking style saying a person with vitamin B12 deficiency can walk unsteadily, or with their feet set wide apart. Similarly, Johns Hopkins Medicine refers to the walking as an “unsteady, staggering” gait - an “ataxic gait” because walking is uncoordinated.

How long does it take to fully recover from B12 deficiency? ›

Once you begin treating your vitamin B12 deficiency, it can take up to six to 12 months to fully recover. It is also common to not experience any improvement during the first few months of treatment. If you can, it's a good idea to address what's causing the deficiency.

What depletes B12 in your body? ›

Diet. Some people can develop a vitamin B12 deficiency as a result of not getting enough vitamin B12 from their diet. A diet that includes meat, fish and dairy products usually provides enough vitamin B12, but people who do not regularly eat these foods can become deficient.

What cancels out vitamin B12? ›

Summary: As summarized in the table provided, vitamin B12 (cobalamin) absorption and utilization by the body can be compromised with the chronic use of certain medications which include: colchicine, chloramphenicol, ethanol, histamine 2 receptor antagonists (H2RA), metformin, and proton pump inhibitors (PPI).

What medications should not be taken with B12? ›

Interactions
  • Aminosalicylic acid (Paser). Taking this drug used to treat digestive problems might reduce your body's ability to absorb vitamin B-12.
  • Colchicine (Colcrys, Mitigare, Gloperba). ...
  • Metformin (Glumetza, Fortamet, others). ...
  • Proton pump inhibitors. ...
  • Vitamin C (ascorbic acid) supplements.

What is the fastest way to fix B12 deficiency? ›

How to raise your B12 levels fast. The most common way to treat B12 deficiencies is by adjusting your diet. If this is unsuccessful, vitamin supplements may be recommended. If you're looking to boost the amount of vitamin B12 in your diet, you should eat more animal products, like meat, seafood, dairy and eggs.

How can I check my B12 level at home? ›

It's possible to test your B-12 levels at home. Home test kits cost about $65.00 to $90.00 each and can be purchased online. Most home kits test your urine for the presence of MMA, which is linked to early stages of a vitamin B-12 deficiency. You may need to send your urine sample to a laboratory.

How long does it take to recover from vitamin B12 deficiency? ›

It is possible to restore your vitamin B12, but it won't happen overnight. It usually takes a few months for most people to see an improvement, which is often gradual. In extreme cases, it can take up to a year to notice the effects of treatment, but in most cases, you'll be looking at around 4 - 6 months.

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