Hyaluronic Acid: What It Is, Benefits, How To Use & Side Effects (2024)

How does hyaluronic acid work?

Hyaluronic acid belongs to a type of long, complicated chain-like molecules called polymers. The chain has plenty of spots on it where other chemical compounds (like water, for example) can latch on. That’s why a quarter-teaspoon of hyaluronic acid can hold about one and a half gallons of water, making it the best polymer — natural or artificial — for absorbing water (and a key ingredient in moisturizing products).

Because it has lots of space for other molecules to latch on, hyaluronic acid is great for transporting other molecules throughout your body. It also has the ability to attach itself to cells, which is why targeted delivery of medications using hyaluronic acid is a major topic of study.

Hyaluronic acid’s chain-like structure also means it can act like a scaffold structure, allowing tissues to grow. This is a key step in how wounds heal on your body. Scientists have also found hyaluronic acid in human embryos and are studying what role hyaluronic acid plays in reproduction and development.

Does hyaluronic acid work?

Yes, depending on how it’s used. It’s a versatile molecule and scientists are still finding new and beneficial ways to use it. Right now, it’s most often used for skin, joint and eye health. It’s also the topic of hundreds of scientific studies and trials around the world.

What does hyaluronic acid do for skin?

Long-term use of hyaluronic acid serum on your skin or in a supplement taken by mouth can improve overall skin health. It’s also great for helping improve overall skin flexibility and elasticity (meaning it makes your skin more stretchy and soft).

Is hyaluronic acid good for acne?

Hyaluronic acid is widely used as an ingredient in fillers that repair or conceal scars left behind by acne. There has been some limited research into combinations of hyaluronic acid and other medications to treat acne, but so far, there isn’t much evidence that these are effective.

Is hyaluronic acid safe?

Yes, depending on how it’s used. Over-the-counter hyaluronic acid serums and products applied on your skin (creams, lotions, etc.) or in eye care products are considered safe. Hyaluronic acid supplements taken by mouth are also considered safe (but you should still tell your healthcare provider about them, as you would for any other medication, vitamin or supplement).

Prescription hyaluronic acid products should be taken exactly as instructed by your healthcare provider. Injections of any kind containing hyaluronic acid should only be given by a licensed, qualified medical professional.

When should I talk to my healthcare provider about hyaluronic acid?

You may want to talk to your healthcare provider about hyaluronic acid if you’re interested in using it as a supplement. You may also want to also ask them about treatment options that use hyaluronic acid for the following conditions or purposes:

  • Skin health (especially dryness, scarring, stiffness and skin diseases like scleroderma and actinic keratosis).
  • Eye health, especially for treating dry eyes.
  • Joint health, especially for treating arthritis and soft tissue injuries.
  • For wounds that are slow to heal.
  • As a treatment option for bladder pain, especially pain caused by interstitial cystitis.
  • Respiratory conditions like asthma.

A note from Cleveland Clinic

Hyaluronic acid has many uses and benefits, from boosting skin, eye and joint health to accelerating wound healing. Like any medication or supplement, it’s important to talk to your healthcare provider before incorporating hyaluronic acid into your healthcare regimen.

Hyaluronic Acid: What It Is, Benefits, How To Use & Side Effects (2024)
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